Selected Publications
Short, James E, Sharek, Lisa, et al. “Gene-sized DNA insertion at genomic safe harbors in human cells using a site-directed transposase” Nucleic Acids Research, in press
Hew, Brian E, Sabranth Gupta, et al. “Directed evolution of hyperactive integrases for site specific insertion of Transgenes.” Nucleic Acids Research, vol. 52, no. 14, 2 July 2024,
Owens, Jesse, et al. “Assessing lifespan and aging phenotypes resulting from FOXO3 induction using Mouse Models.” Innovation in Aging, vol. 5, no. Supplement_1, 1 Dec. 2021, pp. 366–366,
Hew, Brian E, Ryuei Sato, et al. “RNA-guided Piggybac transposition in human cells.” Synthetic Biology, vol. 4, no. 1, 1 Jan. 2019,
Owens, J.B., Urschitz, J., Stoytchev, I., Dang, N.C., Stoytcheva, Z., Belcaid, M., Maragathavally, K.J., Coates, C.J., Segal, D.J. and Moisyadi, S. (2012) Chimeric piggyBac transposases for genomic targeting in human cells. Nucleic acids research, 40, 6978-6991
Owens, J.B., Mauro, D., Stoytchev, I., Bhakta, M.S., Kim, M.S., Segal, D.J. and Moisyadi, S. (2013) Transcription activator like effector (TALE)-directed piggyBac transposition in human cells. Nucleic acids research, 41, 9197-9207.
Urschitz, J., Kawasumi, M., Owens, J., Morozumi, K., Yamashiro, H., Stoytchev, I., Marh, J., Dee, J.A.,Kawamoto, K., Coates, C.J. et al. (2010) Helper-independent piggyBac plasmids for gene deliveryapproaches: strategies for avoiding potential genotoxic effects. Proceedings of the National Academy of Sciences of the United States of America, 107, 8117-8122.
Owens, J.B., Mathews, J., Davy, P., Stoytchev, I., Moisyadi, S. and Allsopp, R. (2013) Effective Targeted Gene Knockdown in Mammalian Cells Using the piggyBac Transposase-based Delivery System. Molecular therapy. Nucleic acids, 2, e137.
Davy, P.M., Lye, K.D., Mathews, J., Owens, J.B., Chow, A.Y., Wong, L., Moisyadi, S. and Allsopp, R.C. (2015) Human adipose stem cell and ASC-derived cardiac progenitor cellular therapy improves outcomes in a murine model of myocardial infarction. Stem cells and cloning : advances and applications, 8, 135-148.
Anderson, C.D., Urschitz, J., Khemmani, M., Owens, J.B., Moisyadi, S., Shohet, R.V. and Walton, C.B.(2013) Ultrasound directs a transposase system for durable hepatic gene delivery in mice. UltrasoundMed Biol, 39, 2351-2361.
Marh, J., Stoytcheva, Z., Urschitz, J., Sugawara, A., Yamashiro, H., Owens, J.B., Stoytchev, I., Pelczar,P., Yanagimachi, R. and Moisyadi, S. (2012) Hyperactive self-inactivating piggyBac for transposase-enhanced pronuclear microinjection transgenesis. Proceedings of the National Academy of Sciences of the United States of America, 109, 19184-19189.
